SL1 RNA

SL1 RNA
Predicted secondary structure and sequence conservation of SL1
Identifiers
Symbol SL1
Rfam RF00198
Other data
RNA type Gene
Domain(s) Eukaryota
GO 0000365
SO 0000233

This family represents the SL1 RNA. SL1 is commonly located in the spacer region between 5S-rRNA genes where it is involved in trans-splicing. Trans-splicing is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an intra-molecular reaction which precisely joins exons derived from separately transcribed RNAs. This mechanism of mRNA maturation has been shown to occur in a number of lower eukaryotes and is commonplace in nematodes[1].

References

  1. ^ Dassanayake, RS; Chandrasekharan NV, Karunanayake EH (2001). "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene 269 (1-2): 185–193. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950. 

External links